Monday, March 4, 2019

An Analysis of the Urban Issue of Tuberculosisin the Bourough of Newham

1.Introduction tebibyte is a actually serious pathogenic complaint that primarily affects the lungs, causing cough and active difficulties. The contagious disease system likewise causes systemic cause including fever, night sweats and angle loss (Ellner, 2011). In around cases, the infection tramp spread beyond the lungs and affect the b angiotensin-converting enzyme/joints, lymph nodes, abdomen and blood stream (Ormerod, 2003). The unhealthiness is caused by the bacteria mycobacterium terbium (WHO, 2014), which is spread through respiratory droplets. These droplets be passed when an infected individual coughs or sneezes and the droplets become inhaled by an early(a) soulfulness (NHS, 2014). Despite this easy method of transmittal, terabyte is non readily transmitted, and thencece is most be handle to affect those in basis out contact much(prenominal) as family or household members (Cast complainto-C stimulatez & Feng). terbium maps a significant danger of morbidity and mortality and represents a significant salute to society to make do and manage. terabyte has particularly shown to be a chore in cities, whereby the judge of increase argon great than those of rural beas (Anderson et al. 2006). This essay will yell the reasons as to why terabit affects urban atomic number 18as (the sick city hypothesis), and reflexion in to why terabyte leaves to this urban health penalty. As an model of an urban environment suffering from the burden of atomic number 65, this essay will charge on the capital of the United Kingdom borough of modernisticham. Newham has a terbium rate 8 times toweringer than the national average and 3 times that of capital of the United Kingdom. This essay aims to enquire the aetiology behind the incidence, and to find ways of reducing the range of terabit among individuals in the capital of the United Kingdom borough of Newham. The paper will include the interjection strategies and how they should be implemented in order to wither the rates of new infections and promote men to get tested and get early interference in advance the spread of infection.2. terbium in an Urban Environment terbium tends to be regarded as a problem of the past, and was responsible for 20-30% of all mortality in 17th-19th nose candy Europe (Dye & Williams, 2010). The incidence of tebibyte declined throughout the 20th century (Watson & Maguire, 1997), heretofore, the illness has been slowly returning to capital of the United Kingdom since the 1980s (Great Britain 2008, p. 19). The problem seems to be declension in urban atomic number 18as. This is illustrated by the manikin of London, where 3,302 new cases of tuberculosis (TB) were report in 2010 (Fullman & Strachan 2013, p. 25), a figure that has more than doubled since 1992 (Anderson et al 2006). In 2006, the incidence of tuberculosis in London was 41.5 battalion in 100,000, a figure that represented the highest number of new cases in a ny study city in western Europe (Anderson et al, 2006). Dyer (2010, p. 34) claims that the London borough of Newham is the most stirred with some quite a little already referring to it as the TB capital of the adequate western world. In fact, the rates of tuberculosis in Newham ar soon higher than that in some impoverished countries. Vassall (2009, p. 48) allude that Newham has 108 cases per 100,000 and Anderson et al suggest a 2001 figure of 116/100,000, figures that are more than half that in India (174 cases per 100,000) (Public wellness England, 2012). Newham has a race of 308,000 with a population density of 85.1 per hectare as compared to 31 in central London (UK numerate, 2012). These figures suggest that even in the dwell city of London, Newham is an area of urbanisation, with a vainglorious number of pile c formerlyntrate into a relatively small area.The increase of tuberculosis has been described as a penalty for high density urban active (Dye 2010, p.859), likely due to the change magnitude potential for transmission in overcrowding, and the increased rates of immigration to inner-city areas. Bhunu and Mushavabasa (2012) propose that tuberculosis thrives in conditions of overcrowding and poverty, issues that are common in urban areas.The high rates of tuberculosis in cities such as London, and areas of urbanization such as Newham, suggest that the incidence of tuberculosis is indeed an urban issue. Newham fulfills the criteria of high immigration rates and world an area of deprivation..Newham has a diverse ethnic population, with 61% of the people being non-white (Farrar & Manson 2013, p. 54). The population of ethnic minorities continues to grow along with the increasing numbers of refugees and asylum seekers in great London.Another aspect of urbanisation illustrated in the borough of Newham is that of deprivation and overcrowding. Farrar & Manson (2013, p. 16) claim that Newham ranks as the third most deprived borough in inner London. Most of the people here live in tower housing and overcrowded conditions that are the consummate condition for the spread of tuberculosis. There is a positive correlation amid poor housing and poverty and the prevalence of tuberculosis, which is very clear in Newham as evidenced by the findings of 108 and 116 cases per 100,000 people (Vassal, 2009 Anderson et al., 2001). The aetiology of the issue of tuberculosis is highlighted when considering the distribution of the disease across Newham. The occurrence of disease is not evenly spread across the borough, with 70% of cases advance from manor house Park, Green thoroughfare and East Ham. These boroughs represent areas of population increase, overcrowding and higher takes of those living in poverty. Manor Park and Green Street also show differing dynamics of tuberculosis incidence, representing an overall increase of 40% since 2006 whilst all other areas of Newham either remained unchanging or showed slight decrease (Ma lone et al 2009, p. 23). It can be seen that tuberculosis presents a significant urban issue, especially when comparing incidence in an urban area such as Newham to those less urbanised areas. Bromley has a population of 309,000 and a population density of 20 per hectare, in comparability to Newhams population density of 80 per hectare (UK Census, 2012). Tuberculosis incidence in Bromley is between 0-19 per 100,000 compared to that of Newham, which is five times greater at 80-100 per 100,000 (Anderson et al., 2006). It is for this reason that needful intervention strategies need to be formulated and implemented to help reduce the rates of tuberculosis among individuals living in Newham.3. The Influence of Urbanisation on Tuberculosis IncidenceWhile the global rates of tuberculosis are declining, the disease is showing steady increase in the United Kingdom. In 2012, 8751 new cases of the disease were identified in the country with 39% coming from London (Fullman and Strachan 2013, p . 43). Indeed London has the highest rates of the disease in Western Europe with Newham borough having the highest rates in the UK. Jindal (2011, p. 55) claims that the rate of tuberculosis in some London boroughs is more than twice higher than the threshold used by the world health organisation to define high rates. These higher incidences documentation the notion of a sick city hypothesis where there are greater levels of ill health than in rural areas, and whitethorn be due to the presence of factors in an urban environment that contribute to ill health (an urban health penalty). One factor that may contribute to the urban health penalty is that of immigration. Cities are easier to retrieve than rural areas, bring home the bacon areas of congregation and provide more facilities for immigrating families and individuals. The majority of individuals suffering from tuberculosis are people born outside the United Kingdom, with 75% of cases in 2003 being born abroad (Anderson et al. , 2006). A reason for the high incidence in those born abroad but now living in the UK is exacerbated by the nature of tuberculosis. On initial infection, tuberculosis is confined by the insubordinate system with only if around 5% of cases experiencing symptoms within the first ii classs of infection (Narasimhan et al., 2013). The remainder of cases harbour a potential infection which may reactivate later in life, with about 10-15% of those infected waiver on to develop an active disease (Narasimhan et al., 2013). This insidious nature combine with the later activation of the disease explains why many people do not get the disease until later in life. It is likely that it is assure in their country of birth, however then manifests much later once they discombobulate moved to the UK. Statistics indicate that over 90% of the residents in Newham diagnosed with the disease in 2011 were born outside the United Kingdom (Fullman and Strachan, 2013, p. 33). Among these, 50% arrived in the country in the last five years. In the same year tuberculosis diagnosing increased by 25% compared to 2010 (Fullman and Strachan, 2013), possibly as a reflection of the increased immigration. Additionally to a high immigrant population bringing significant disease burden from their countries of birth, London and Newham two represent many of the other issues of urbanisation and urban health penalty that can contribute to the high incidence of tuberculosis. Studies have shown that low vitamin D levels are associated with an increased lay on the line of developing tuberculosis (Campbell and Spector, 2012 Chan, 1999). This is an significant association in urban populations, as the living and working conditions foster less access to sunlight (the major source of vitamin D). Additionally, Asian immigrants present a problem of low vitamin D due to vegetarian diets, and a tendency to cover up their skin, not allowing to put one over advantage of the small amount of sunlight rea dy(prenominal) (Chan, 1999). As previously mentioned, Newham is an area of twain high urbanisation and with a large immigrant population, and 38.6% of the population being of Asian descent (London Borough of Newham, 2010). The immigrant population of urban areas such as Newham also present a non-vaccinated proportion of society. Whilst the BCG vaccinum against tuberculosis was introduced in the UK in the 1950s and was shown to provide a step-down in risk of contracting tuberculosis (Colditz et al., 1994), those immigrating were less likely to bump this vaccination on moving to the UK. London also represents cases of tuberculosis that are socially and medically Byzantine. As a hugely populated area, London includes those with HIV infection and presents other risk factors such as frontwards transmission and poor treatment. HIV is one of the most powerful risk factors for tuberculosis, with a incidence rate of 20 times higher in those that are HIV positive (Dye and Williams, 201 0). Peoples places towards and access to health care also present a complex mix of factors which contribute to an increased incidence of many health problems, including that of tuberculosis. Those in impoverished areas have decrease access to healthcare, which may stem from many reasons such as complex of necessity, chaotic lifestyles, location of services, user ignorance, and language and literacy barriers (Szczepura, 2005). These can affect the disease process of tuberculosis from measure, treatment of active disease, shackle to treatment and keep openion of the health consequences. Especially problematic are misconceptions and a lack of intellect of the disease, leading to late presentation and delayed access to treatment (Figuera-Munoz and Ramon-Pardo, 2008) With the close living quarters in areas such as Newham, the spread of tuberculosis is facilitated. With poverty, poor housing and overcrowding, these areas concentrate several risk factors and lead to a greater spread of tuberculosis (Bates et al., 2004). These determinants therefore suggest that the incidence of tuberculosis in urban areas is a complex issue. Controlling and preventing tuberculosis in London requires hard-hitting social and economic tools that must be corporal in the development of policies of control in treatment initiation.4. Consequences and implications of tuberculosis on the general populationTuberculosis ranks with HIV/ AIDS and Malaria as one of the three main health challenges currently facing the world. The Commonwealth wellness Ministers modify 2009 (2009, p. 41) indicates that 8 million new cases are reported globally each year. As previously mentioned, when combined with HIV, tuberculosis can produce lethal as the two diseases enhance the progress of each other. It is for this reason that tuberculosis is the major cause of death among HIV patients with the rate standing(a) at 11% globally. The earth health Organization (2009, p. 27) indicates that tuberculosis is responsible for more deaths today than ever before, with approximately 2 million lives claimed by the disease annually. As well as the significant mortality contributed by tuberculosis, the morbidity of the disease can be extremely detrimental both socially and economically. Those with the active disease that are not receiving treatment have been shown to go on to infect 10-15 others every year (WHO, 1998). Those who do achieve treatment face a long (up to six months) and complex treatment administration involving several medication side effects. This can affect adherence to the treatment regime, and lead to the disease developing a resistance to the treatment, with this medicate resistant tuberculosis alter to greater mortality and increased get down to treat (Ahlburg, 2000). As well as the significant morbidity and mortality, it is important to consider the economic impact of tuberculosis. The World Health Organisation estimated the cost to treat tuberculosis in 2000 as $ 250,000 US dollars (?150,000) in developed countries (Ahlburg, 2000). This presents a significant burden to the UK NHS, not to mention the time confounded through not working which can dent the economy. London is a global world trade centre whose economy is shaped by global forces, particularly in terms of trade, labour and capital. As a gateway to both the UK and other parts of Europe and the rest of the world, London records a very large number of tourists and immigrant populations. This high number of people accelerates the spread of the disease as people carry it to the country from other parts of the world is indicated by the new infection patterns and is highlighted by the prevalence in immigrant populations. 5. Strategies and intervention for addressing tuberculosis latest UK guidelines for tuberculosis intervention were do by NICE in 2006 (updated 2011). The recommendations propose strategies for identifying those with latent (non-active) tuberculosis to prevent spread or reactivation and also specify criteria for treatment (NICE, 2011). Those recommended for screening for latent tuberculosis include close contacts of infected individuals, immigrants from high incidence countries, immunocompromised individuals, and healthcare workers. Whilst this strategy targets prevention of the spread of tuberculosis, they are only targeting ad hoc groups, and it is likely in high incidence areas such as Newham, people will slip through the net. These guidelines have only changed minimally since 2006, and since then tuberculosis incidence has been on the increase in areas such as Newham, suggesting that changes may need to be made. High incidence areas of the UK such as Newham could learn from New York experience and copy the strategy it used in dealing with the disease. With the implementation of broadened initial treatment regimes, direct observed therapy, and better guidelines for hospital control and disease prevention, the city managed to halt the progressi on of an epizootic (Frieden et al., 1995). As mentioned in the previous chapter, adherence to the lengthy treatment regime as well as a lack of understanding may contribute to the spread of tuberculosis. Directly observed therapy (DOT) involves observing the patient take each dose of their medication, with outreach workers travelling to their homes. Evidence from New York showed that through DOT, only 3% of patients in therapy were infectious, compared to a proposed 20% if not receiving DOT (Frieden et al., 1995). Current UK guidelines (NICE, 2006) do not recommend DOT, although they do state that it may be used in cases of patients with previous issues with adherence or at high risk. Although an expensive and time consuming process, if DOT can reduce infectious cases, this would also work as a preventative measure. There could be one allocated outreach nurse for the borough of Newham and other high-risk areas. Another method implemented in New York was the downsizing of large shel ters for the homeless. These were breeding grounds for tuberculosis, and the ensuant reduction in overcrowding led to a decrease in transmission of the disease (Frieden et al., 1995). Whilst it is not likely to split people up from living with their families in crowded homes in terms of Newham, education about tutelage those with tuberculosis from interacting with too many others in crowded conditions may be of benefit. The model should also borrow from those used by other cities like Paris and the rest of Europe in controlling tuberculosis with intervention at the level of the agent, individual and community levels. In Paris, Rieder (2002) suggested that prophylactic treatment could be used to prevent the disease occurring in those at risk, for example those in the household of an identified case of tuberculosis. Additionally, Rieder (2002) proposed that early or newborn vaccination be used especially in those in areas where tuberculosis is frequent, rarely diagnosed, and adequa te contact examinations rarely feasible. It may be possible that in cases where lots of people are vaccinated that they may deduct herd immunity and thus protect unvaccinated individuals from the disease. Once the populations have been protected and the incidence (number of new cases) of tuberculosis has been reduced, this allows for a reduction in the prevalence of tuberculosis (number of ongoing cases at any one lodge in time) with preventative chemotherapy that can treat sub-clinical, latent tuberculosis in the population. This preventative chemotherapy is likely to be extremely relevant to Newham due to the large immigrant population likely harbouring latent tuberculosis. On a country- or city-wide scale, these recommendations from New York and Paris provide excellent models for preventing the increase of tuberculosis any further. It is also important, however, to consider the individual communities in Newham, and to promote health awareness and an attitude towards taking resp onsibility for their health. Their needs to be an furtherment at the level of primary care where immigrant populations feel that they can approach healthcare, and education to encourage tuberculosis prevention and adherence to treatment. The strategy should be all-inclusive in order to encourage people to not only go for interrogatory but also start and finish the treatment process.6. Recommendations and conclusionTuberculosis presents an important urban issue in the area of Newham. Incidence is greater than other areas of the UK, and is over half that of India. There are several factors contributing to this including a large immigrant population, crowding and overpopulation, access to healthcare and comorbid health problems such as vitamin D deficiency and HIV. The disease has considerable effect on morbidity and is responsible for high levels of mortality. Further consequences of the disease manifest as economic problems such as cost of treatment and loss of work. London and the UK already have policies and structures for controlling tuberculosis in place however the implementation process is patchy across the city, and often dependent upon budget. In high-risk areas such as Newham, there is poor access of healthcare due to inaccurate beliefs on the disease, language and cultural barriers, and complex needs of the population. In the case of tuberculosis, these contribute to poor disease prevention, delayed diagnosis and poor treatment adherence. All of which lead to an increase in transmission and health consequences. The area of Newham would benefit greatly from further education into tuberculosis, how to notion for signs and how to get treatment. Encouraging good relationship with healthcare professionals and promoting access to healthcare through outreach programmes and targeting pharmacies may be helpful. Additionally, Newham should look to employ techniques used in New York and Paris, including DOT, prophylactic treatment and neonate vaccination to r educe both the prevalence and incidence of tuberculosis.ReferencesAhlburg (2000). The economic impact of TB ministerial multitude Amsterdam, WHO Bates, I., Fenton, C., Gruber, J., Lalloo, D., Lara, A. M., Squire, S. B., and Tolhurst, R. (2004). Vulnerability to malaria, tuberculosis, and HIV/AIDS infection and disease. Part II determinants operational at environmental and institutional level. The Lancet Infectious Diseases, vol. 4(6), pp. 368-375. Bhunu, C. P., and Mushayabasa, S. (2012). Assessing the effects of poverty in tuberculosis transmission dynamics. Applied numeral Modelling, vol. 36(9), pp. 4173-4185.Campbell, G. R., and Spector, S. A. (2012). Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy. PLoS pathogens, vol. 8(5).Castillo-Chavez, C., and Feng, Z. (1997). To treat or not to treat the case of tuberculosis. diary of mathematical biology, vol. 35(6), pp. 629-656.Colditz , G. A., Brewer, T. F., Berkey, C. S., Wilson, M. E., Burdick, E., Fineberg, H. V., and Mosteller, F. (1994). Efficacy of BCG vaccinum in the prevention of tuberculosismeta-analysis of the published literature. Jama, vol. 271(9), pp. 698-702. Commonwealth Health Ministers Update 2009. (2009). Commonwealth Secretarial. Dye, C., and Williams, B. G. (2010). The population dynamics and control of tuberculosis. Science, vol 328(5980), pp. 856-861. Dyer, C. A. (2010). Tuberculosis. Santa Barbara, California Greenwood. Ellner JJ. Tuberculosis. In Goldman L, Schafer AI, eds. Goldmans Cecil Medicine. 24th ed. Philadelphia, PA Elsevier Saunders 2011 vol332. Farrar, J., & Manson, P. (2013). Mansons tropical diseases. Hoboken, NJ Wiley. Figueroa-Munoz, J. I., & Ramon-Pardo, P. (2008). Tuberculosis control in vulnerable groups. Bulletin of the World Health Organization, 86(9), 733-735.Frieden, T. R., Fujiwara, P. I., Washko, R. M., and Hamburg, M. A. (1995). Tuberculosis in New York Cityturning the tide. New England Journal of Medicine, vol. 333(4), pp. 229-233. Fullman, J., & Strachan, D. (2013). Frommers London 2013. Hoboken, NJ Wiley. Great Britain. (2008). Diseases know no frontiers How effective are intergovernmental organisations in controlling their spread 1st report of session, 2007-08. London Stationery Office. Jindal, S. K. (2011). Textbook of pulmonary and critical care medicine. New Delhi Jaypee Brothers aesculapian Publishers. London Borough of Newham, (2010). Community Leaders and Engagement, Manor Park Community gathering Profile Online, Availablehttp//www.newham.info/research/CFProfiles/ManorPark.pdf 12 April 2014. Malone, C., Beasley, R. P., Bressler, J., Graviss, E. A., Vernon, S. W., & University of Texas Health Science Center at Houston, School of Public Health. (2009). Trends in anti-tuberculosis drug resistance from 20032007 at Pham Ngoc Thach Tuberculosis and Lung Disease Hospital, Ho Chi Minh City, Vietnam. (Masters Abstracts International, 47-5. ) National add for Health and kick Excellence (2006) Clinical Diagnosis and Management of Tuberculosis, and measures for its prevention and control. CG117. London National Institute for Health and Care Excellence.Ormerod, L.P. (2003) Nonrespiratory tuberculosis. In Davies PDO (Ed) Clinical Tuberculosis. Third Edition. Arnold London. pp. 125-153. Public Health England (2012), World Health Organization (WHO) estimates of tuberculosis incidence by rate, 2012 (sorted by rate). Online Available at http//www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1317140584841 12 April 2014. Rieder, H. A. (2002). Interventions for Tuberculosis Control, 1st edn. International Union Against Tuberculosis and Lung Disease, Paris, France.Szczepura, A. (2005). Access to health care for ethnic minority populations. Postgraduate medical exam Journal, vol. 81(953), pp. 141-147. Vassall, A., & University of Amsterdam. (2009). The Costs and cost-effectiveness of tuberculosis control. Amsterdam Amsterdam University P ress. Watson, J. M., and Maguire. H.C (1997). PHLS work on the supervision and epidemiology of tuberculosis. Communicable disease report. CDR review 7.8, pp. R110-2. World Health Organization. (2009). Global tuberculosis control Epidemiology, strategy, financing WHO report 2009. Geneva World Health Organization. World Health Organisation (2014). Tuberculosis. Online, Available http//www.who.int/topics/tuberculosis/en/ 12 April 2014 UK Census (2012), UK Census Data, Online. http//www.ukcensusdata.com/newham-e09000025sthash.51Phmj6a.dpbs 12 April 2014

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.